• 智能影像诊断及转化应用

• 生物医学工程

• 上海市科学技术委员会，脑卒中多中心多模态影像数据库的建立及人工智能产品的评价体系研究，2019年-2022年；

• 上海市科学技术委员会，人工智能在脑恶性肿瘤影像诊断中的应用研，2017年-2020年；

• 上海市科学技术委员会，基于数据库的脑肿瘤多模态影像学精确诊断与预后评估，2016年-2019年；

• 国家自然科学基金委员会，IDH1 基因突变胶质瘤的多模态MRI 特征及其机制研究，2015年-2018年；

• 国家自然科学基金委员会，TRAIL 基因靶向诱导鼠脑胶质瘤凋亡的功能MRI及病理机制研究，2011年-2013年

出版专著

1. 《影像专家鉴别诊断-颅脑与脊柱脊髓分册》、《脊柱与脊髓影像诊断学》、《颅脑影像鉴别诊断学》、《脑与脊髓肿瘤影像学》

发表论文

• Endovascular management of giant middle cerebral artery aneurysms., Int J Clin Exp Med, 8, 7517-25.

• Intracranial Blood Flow Changes in Patients with High-Grade Severe Carotid Artery Stenosis After Stenting., World Neurosurg, 104, 863-868.

• Prediction of Reperfusion-Associated Hemorrhagic Transformation Using Dynamic Contrast-Enhanced Imaging in a Rat Stroke Model[J]. Journal of Computer Assisted Tomography, 2015, 39(5):787-793.

• Intracranial Blood Flow Changes in Patients with High-Grade Severe Carotid Artery Stenosis After Stenting., World Neurosurg, 104, 863-868.

• Prediction of Reperfusion-Associated Hemorrhagic Transformation Using Dynamic Contrast-Enhanced Imaging in a Rat Stroke Model[J]. Journal of Computer Assisted Tomography, 2015, 39(5):787-793.

• The diagnostic value of texture analysis in predicting WHO grades of meningiomas based on ADC maps: an attempt using decision tree and decision forest., Eur Radiol, 29, 1318-1328.

• Neuroradiological features of papillary glioneuronal tumor: a study of 8 cases., J Comput Assist Tomogr, 38, 634-8.

• Diffusion-weighted imaging of the sellar region: a comparison study of BLADE and single-shot echo planar imaging sequences., Eur J Radiol, 83, 1239-1244.

• Combination of diffusion tensor imaging and conventional MRI correlates with isocitrate dehydrogenase 1/2 mutations but not 1p/19q genotyping in oligodendroglial tumours., Eur Radiol, 26, 1705-15.

• Evaluation of the applicability of territorial arterial spin labeling in meningiomas for presurgical assessments compared with 3-dimensional time-of-flight magnetic resonance angiography., Eur Radiol, 27, 4072-4081.

• Presurgical differentiation between malignant haemangiopericytoma and angiomatous meningioma by a radiomics approach based on texture analysis., J Neuroradiol, 46, 281-287.

• The diagnostic value of texture analysis in predicting WHO grades of meningiomas based on ADC maps: an attempt using decision tree and decision forest[J]. European Radiology, 2019,29(3):1318-1328.

• MR imaging features of spinal pilocytic astrocytoma[J]. BMC Medical Imaging, 2019,19(1):2-8.

• The role of three-dimensional pseudocontinuous arterial spin labelling in grading and differentiating histological subgroups of meningiomas[J]. Clinical Radiology, 2018, 27 (2):176-184.

• Evaluation parameters between intra-voxel incoherent motion and diffusion-weighted imaging in grading and differentiating histological subtypes of meningioma: A prospective pilot study[J]. Journal of the Neurological Sciences, 2017,372:60-69.

• Evaluation of the applicability of territorial arterial spin labeling in meningiomas for presurgical assessments compared with 3-dimensional time-of-flight magnetic resonance angiography[J]. European Radiology, 2017,27(10):4072-4081.

• Noninvasively detecting Isocitrate dehydrogenase 1 gene status in astrocytoma by dynamic susceptibility contrast MRI[J]. Journal Magnetic Resonance Imaging, 2017,45(2):492-499.

• Differentiating Primary Central Nervous System Lymphomas From Glioblastomas and Inflammatory Demyelinating Pseudotumor Using Relative Minimum Apparent Diffusion Coefficients[J]. Journal of computer assisted tomography, 2017,41(6):904-909.

• Diffusion-Weighted Imaging for Predicting and Monitoring Primary Central Nervous System Lymphoma Treatment Response[J]. American Journal of Neuroradiology, 2016,37(11):2010-2018.

• Combination of diffusion tensor imaging and conventional MRI correlates with isocitrate dehydrogenase 1/2 mutations but not 1p/19q genotyping in oligodendroglial tumours[J]. European Radiology, 2016,26(6):1705-1715.

• Detecting isocitrate dehydrogenase gene mutations in oligodendroglial tumors using diffusion tensor imaging metrics and their correlations with proliferation and microvascular density[J]. Journal of Magnetic Resonance Imaging, 2016,43(1):45-54.

• Prediction of the consistency of pituitary adenoma: A comparative study on diffusion-weighted imaging and pathological results[J]. Journal of Neuroradiology, 2016,43(3):186-194.

• Neuroradiological features of papillary glioneuronal tumor: a study of 8 cases[J]. Journal of computer assisted tomography, 2014,38(5):634-638. (24)TAZ expression on endothelial cells is closely related to blood vascular

• density and VEGFR2 expression in astrocytomas[J]. Journal of Neuropathology & Experimental Neurology, 2019,78(2):172-180.

• A multimodal Pepstatin A peptide-based nanoagent for the molecular imaging of P-glycoprotein in the brains of epilepsy rats., Biomaterials, 76, 173-86.

• Construction of Pepstatin A-Conjugated ultrasmall SPIONs for targeted positive MR imaging of epilepsy-overexpressed P-glycoprotein., Biomaterials, undefined, 119581.

• Engineered superparamagnetic iron oxide nanoparticles (SPIONs) for dual-modality imaging of intracranial glioblastoma via EGFRvIII targeting [J].Beilstein journal of nanotechnology,2019, 10, 1860-1872.

• Conventional and Diffusional Magnetic Resonance Imaging Features of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes inChinese Patients: A Study of 40 Cases., J Comput Assist Tomogr, 42, 510-516.

• Use of oral anticoagulant drugs is associated with carotid intraplaque hemorrhage in atherosclerosis patients: a meta-analysis [J]. Journal of thrombosis and thrombolysis,2019

• Radial diffusivity as an imaging biomarker for early diagnosis of non-demented amyotrophic lateral sclerosis[J]. European Radiology. 2018, 28(12):4940~4948

• Intracranial Blood Flow Changes in Patients with High-Grade Severe Carotid Artery Stenosis After Stenting[J], World Neurosurgery, 2017:104:863-868

• Endovascular management of giant middle cerebral artery aneurysms[J]. International Journal of Clinical & Experimental Medicine.2015, 8(5):7517-7525.

• Endovascular coil embolization of aneurysm neck for the treatment of ruptured intracranial aneurysm with bleb formation[J]. Med Sci Monit, 2014; 20: 1121-1128.

• 新型冠状病毒肺炎的CT 征象，上海医学，1-10[2020-04-15]

• 功能磁共振成像在狼疮性脑病诊治中的研究进展[J].中国临床神经科学,2019,27(03):347-355+360.

• 磁共振成像诊断常见中枢神经系统脱髓鞘疾病的研究进展[J].神经病 学与神经康复学杂志,2019,15(01):46-52.

• 健康扶贫中的医务社会工作[J].中国社会工作,2017(27):4-6.

• 1996年8月至现在，复旦大学附属华山医院放射科；

• 1984年7月至1996年7月，徐州医学院附属医院放射科

• 中国医师协会放射分会委员

• 中国女医师协会常务理事兼医学影像专业委员会主任委员

• 上海市医师协会影像医学与核医学科分会会长

• 上海市医学会卒中专业委员会副主任委员

• 上海市女医师协会副会长

• 中国医学装备协会磁共振成像装备与技术专委会副主任委员兼人工智能专委会主任委员等

• 以第一完成人获国家科技进步二等奖、上海市科技进步一等奖、教育部科技进步一等奖等